# amide

Pronunciation: say "AM-yd" /ˈæ.maɪd/

## Noun

1. A derivative of an oxoacid in which the hydroxyl group is replaced by an amino or substituted amino group, especially the carboxamides formed from carboxylic acids.
   - Simple: A kind of chemical formed when a nitrogen-based group takes the place of the -OH part in an acid.
   - _Each peptide bond in a protein is an amide formed between two amino acids._
   - _Acetamide is the simplest amide derived from acetic acid._
2. An ionic derivative of ammonia in which a hydrogen atom has been replaced by a metal cation, yielding anions such as R-NH⁻ or R₂N⁻.
   - Simple: A chemical formed when a metal takes the place of a hydrogen atom in ammonia.
   - _Sodium amide is prepared by dissolving sodium metal in liquid ammonia._
   - _Potassium amide acts as an extremely strong base in many reactions._

## Origin

Formed from "ammonia" combined with the suffix "-ide".

Source: DictionaryAI, https://dictionaryai.com/define/amide (written from Wiktionary data, CC BY-SA 4.0: https://creativecommons.org/licenses/by-sa/4.0/).