annihilate

Short definition from Wiktionary

Verb

1. 1
   To reduce to nothing, to destroy, to eradicate.
2. 2
   To react with antimatter, producing gamma radiation and (for higher-mass reactants, especially composite particles such as protons) lighter particles (such as pions, muons, and neutrinos).
3. 3
   To treat as worthless, to vilify.
4. 4
   To render null and void; to abrogate.