lose it

Short definition from Wiktionary

Verb

1. 1
   To be overcome with emotion: To become explosively angry; to lose one's temper.
2. 2
   To be overcome with emotion: To feel devastated, or distraught, especially when one's sadness is overwhelming.
3. 3
   To be overcome with emotion: To begin to laugh uncontrollably.
4. 4
   To be overcome with emotion: To lose one's mind, go crazy.
5. 5
   To cease to have a skill or ability, to lose one's touch, to be washed up.
6. 6
   To lose control of a situation.
7. 7
   Used other than figuratively or idiomatically: see lose, it.