setback

Short definition from Wiktionary

Noun

1. 1
   An obstacle, delay, disadvantage, or blow (an adverse event which slows down, or prevents progress towards a desired outcome).
2. 2
   Any adverse event, defeat, or impediment of progress.
3. 3
   The required distance between a structure and a road.
4. 4
   A step-like recession in a wall.
5. 5
   An offset to the temperature setting of a thermostat to cover a period when more or less heating is required than usual.
6. 6
   A backset; a countercurrent; an eddy.
7. 7
   A backset; a check; a repulse; a relapse.